Darwinism applies to all living things.
It learned to burrow to survive threats, and whatever else they do to survive. I'm not a mouse-ologist, but it was the first small animal that came to mind for that example. Some of the survival traits are passed on via instinct, others via learning from their elders.
As for fat, lazy humans, I'd say that human compassion has made us defy "survival of the fittest". I'd say it originally rewarded the strong by allowing them to be the only ones to survive to breeding age. Or, like lions, only the strongest were allowed to breed, because the strong wouldn't allow the weak to touch the women. This also happens with other pack animals. Again, not a biologist, so I'm not gonna get too far into this, but I'd say exemptions are hard to list. Eventually, human compassion and medical advances meant that nearly everyone can survive to breeding age. Now, only the ability to breed is rewarded with furthering the species. If you've seen idiocracy, you've seen this idea at it's most ludacris, and yet it drives the point home pretty clearly. Basically, those concerned with being financially capable of raising a family are cautious and patient to do so, and only have a small number of children, if any at all. These are generally the smartest people. The people who don't concern themselves with things like "success" and "well-being" have children young, and they have a lot of them. Since doctors basically don't allow natural selection to run its course, when these people blow their genitals off with fireworks, doctors save them so they can still mate. There is no natural selection anymore, just people breeding and breeding.
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