While the "running empty" senario is possible, it's not very likely to happen.
I have yet to run the tank dry.
I buy a 5 gallon can of methanol, pour half into the old/empty can, and then fill both cans up with distilled water.
10 gallons last me about 4 months.
And that's with me driving HWY 49 2X a day.
Even during a track day, I only used ~1/2 tank.